buy winstrol

Stanozolol

Stanozolol (also referred to by its brand name Winstrol) is a synthetic anabolic and androgen steroid used medically to treat hormone deficiencies and certain blood disorders, more commonly referred to as Winstrol.

Medical uses

• Treatment of hypoplastic anemia

• Promoting weight gain in HIV/AIDS patients

• Management of hereditary angioedema (off-label use)

Non-medical uses

Bodybuilders and athletes frequently utilize these substances to increase muscle mass, enhance strength, and extend endurance - often leading to doping violations in sports.

Side effects

• Androgenic effects: Acne, hair loss, voice deepening

• Hepatotoxicity (liver dysfunction)

• Clinical Masculinization Syndrome in women

• Elevated blood pressure

Pharmacology

Pharmacodynamics

Binds to androgen receptors to promote protein synthesis. Due to structural modifications, its androgenic activity is reduced compared to that of testosterone.

Pharmacokinetics

• Orally bioavailable with first-pass metabolism in liver

• Half-life of 9 hours (oral tablets) and 24 hours (injectable form)

• Metabolized into stanozolol-17β-carboxylic acid via cytochrome P450 enzymes

Chemistry

Synthesis

Synthesized in 1960s through modification of dienones. Key intermediate involves cyclization of stanozolone derivatives.

Detection in body fluids

• Identified via urine testing using GC-MS and LC-MS/MS

• Metabolites persist for up to 4 weeks post-use

History

Developed by Winthrop Laboratories in 1962. Approved by FDA in 1967 under brand name Winstrol.

Society and culture

Generic names

• Stanozol

• Stanozololum

Brand names

• Winstrol (tablets/injections)

• Winthrop Stanozolol

Legal status

Scheduled as a Schedule III controlled substance under CSA for anabolic steroid regulations. Requires prescription.

Doping in sports

Banned by World Anti-Doping Agency (WADA) since inception of prohibited list. Sanctioned athletes face disqualification and suspensions.

Research

Investigated for potential use in treating muscle-wasting conditions. Studies explore its role in pediatric growth disorders with caution due to side effects.

References

• Clinical Pharmacology Database

• FDA Approved Drug Products List

• World Anti-Doping Agency Prohibited List